Some drug combinations are riskier than others, and some people are more susceptible to developing serotonin syndrome. Doctors report that combining pimozide and Zoloft can further increase the levels of pimozide in the bloodstream, which can affect the heart.
People combining these drugs have an increased risk of a heart problem called QTc prolongation. QTc prolongation is a condition that affects the heart rhythm. Doctors detect it using an electrocardiogram, or ECG. This prolongation can cause a severe heart rhythm condition, called ventricular fibrillation , or sudden cardiac death.
Zoloft can increase the risk of bleeding. Zoloft is safe early in a pregnancy, but in the third trimester, doctors need to weigh the benefits with the potential risks to the fetus.
A baby exposed to Zoloft late in the third trimester has a risk of developing complications that may require a hospital stay. Some babies experience discontinuation syndrome, and doctors need to monitor babies who were exposed to Zoloft late in pregnancy.
Women who are breastfeeding can take Zoloft because the body releases only low amounts into breastmilk. The liver digests Zoloft. People with liver failure can take Zoloft, but doctors may need to adjust the dosage. If someone has mild liver failure, the doctor will prescribe half the usual dosage, for example. Depending on the severity of the side effects, doctors may lower the dosage or recommend a different antidepressant.
Stomach and digestive side effects usually depend on the dosage that a person is taking and often go away after a few weeks. If the drug is causing an upset stomach , take it with food. Sleep disturbances and agitation also tend to decrease over time.
People who experience sleeplessness with Zoloft should try taking the drug in the morning. Others who feel fatigued when taking Zoloft may find that it helps to take the drug at night. Sexual dysfunction in males is a side effect of this and other antidepressants, except bupropion Wellbutrin and buspirone Buspar. Find out about the different types of antidepressants, how they work, any adverse effects, when you can take them, and the alternatives available.
Long-term, it can also affect their body in ways that may be serious. In this article…. How do antidepressants cause sexual side effects and what are the side effects in men and women? Which antidepressants cause fewer sexual side effects?
What to know about overdosing on antidepressants. Medically reviewed by Zara Risoldi Cochrane, Pharm. Is it possible? Signs and symptoms Emergency treatment If you suspect an overdose Recommended and unsafe dosages Suicide prevention Summary Some people with depression take prescription antidepressant medication as a way to manage the condition.
Share on Pinterest Taking too many antidepressants at once may be life-threatening. Signs and symptoms. Share on Pinterest Mild symptoms of an overdose of antidepressants can include nausea, vomiting, and fever.
Emergency treatment. What to do if you suspect an overdose. Recommended and unsafe dosages. Share on Pinterest A person must stick to the dosage of antidepressants that their doctor recommends. Suicide prevention. Latest news Could 'cupping' technique boost vaccine delivery?
Scientists identify new cause of vascular injury in type 2 diabetes. Adolescent depression: Could school screening help? Related Coverage. How can antidepressants affect weight gain? Ashby, MA. Baldwinville, MA. Ottawa, ON. Bethlehem, CT. Calverton, NY. New York City, NY.
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Patients should always follow medical directions when they take Zoloft. There are also many options for treatment for people who need help with overcoming Zoloft dependence. Start the road to recovery. Get a Call. Questions about treatment? Call now for: Access to top treatment centers Caring, supportive guidance Financial assistance options Addiction Center is not affiliated with any insurance.
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I Accept Show Purposes. Table of Contents View All. Table of Contents. Overdose Definition. Possible Complications. Getting Medical Assistance. Next Steps. How to Help After an Antidepressant Overdose. Was this page helpful? Thanks for your feedback! Sign Up. What are your concerns? Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
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